A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint
Eye Drops The acquisition of movable jaws was a major event during vertebrate evolution.The role of NK3 homeobox 2 (Nkx3.2) transcription factor in patterning the primary jaw joint of gnathostomes (jawed vertebrates) is well known, however knowledge about its regulatory mechanism is lacking.In this study, we report a proximal enhancer element of Nk